Controlling hospital-acquired infection due to carbapenem-resistant enterobacteriaceae (CRE)

Mitchell J. Schwaber; Yehuda Carmeli; Stephan Harbarth

doi:10.1007/978-1-4419-1734-8_9

Controlling hospital-acquired infection due to carbapenem-resistant enterobacteriaceae (CRE)

Mitchell J. Schwaber^*, Yehuda Carmeli, Stephan Harbarth

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

CRE impede effective therapy of patients with Gram-negative infections. They affect patients with poor functional status, prolonged hospital stay and multiple exposures to different antibiotic agents. Detecting carbapenemase-mediated carbapenem resistance is a challenge for many microbiology laboratories using automated susceptibility testing systems. To prevent nosocomial and community transmission of CRE, we recommend strict infection control measures-including contact isolation, cohorting of carriers, and dedicated staffing-alongside active surveillance of patients at risk for carriage. Little is known regarding the added value of antibiotic stewardship interventions to control epidemic or endemic transmission of CRE.

Original language	English
Title of host publication	Antibiotic Policies
Subtitle of host publication	Controlling Hospital Acquired Infection
Publisher	Springer New York
Pages	105-115
Number of pages	11
Volume	9781441917348
ISBN (Electronic)	9781441917348
ISBN (Print)	1441917330, 9781441917331
DOIs	https://doi.org/10.1007/978-1-4419-1734-8_9
State	Published - 1 Dec 2012
Externally published	Yes

Keywords

Acinetobacter
Antibiotic resistance
KPC
Metallo beta-lactamase
OXA
Pseudomonas

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10.1007/978-1-4419-1734-8_9

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abstract = "CRE impede effective therapy of patients with Gram-negative infections. They affect patients with poor functional status, prolonged hospital stay and multiple exposures to different antibiotic agents. Detecting carbapenemase-mediated carbapenem resistance is a challenge for many microbiology laboratories using automated susceptibility testing systems. To prevent nosocomial and community transmission of CRE, we recommend strict infection control measures-including contact isolation, cohorting of carriers, and dedicated staffing-alongside active surveillance of patients at risk for carriage. Little is known regarding the added value of antibiotic stewardship interventions to control epidemic or endemic transmission of CRE.",

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AB - CRE impede effective therapy of patients with Gram-negative infections. They affect patients with poor functional status, prolonged hospital stay and multiple exposures to different antibiotic agents. Detecting carbapenemase-mediated carbapenem resistance is a challenge for many microbiology laboratories using automated susceptibility testing systems. To prevent nosocomial and community transmission of CRE, we recommend strict infection control measures-including contact isolation, cohorting of carriers, and dedicated staffing-alongside active surveillance of patients at risk for carriage. Little is known regarding the added value of antibiotic stewardship interventions to control epidemic or endemic transmission of CRE.

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KW - Antibiotic resistance

KW - KPC

KW - Metallo beta-lactamase

KW - OXA

KW - Pseudomonas

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Controlling hospital-acquired infection due to carbapenem-resistant enterobacteriaceae (CRE)

Abstract

Keywords

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