Controlled Deposition of a Functional Piezoelectric Ultra-Aromatic Peptide Layer

Gal Finkelstein-Zuta, Rotem Shitrit, Sharon Gilead, Sigal Rencus-Lazar, Ehud Gazit

Research output: Contribution to journalArticlepeer-review


Peptide assemblies have attracted significant attention due to their high piezoelectric performance and biocompatibility. However, since piezoelectricity is an orientation-dependent property, the alignment of these structures presents a major challenge for their use in piezoelectric applications. We recently showed an ultra-aromatic peptide derivative termed Boc−Dip−Dip to exhibit notably high piezoelectric properties. Here, by obtaining an aligned Boc−Dip−Dip array, we were able to realize the potential of the peptide to form an active piezoelectric layer. The voltage coefficient of the piezoelectric layer calculated using an in-house measurement set-up was more than 2-fold higher compared to poled polyvinylidene−fluoride, the gold standard for piezoelectric biocompatible materials. Our findings pave the way for the utilization of novel piezoelectric biomaterials, bearing the potential to replace lead-based toxic piezoelectric materials, especially in the field of bio-application.

Original languageEnglish
JournalIsrael Journal of Chemistry
StateAccepted/In press - 2022


  • Crystal growth
  • Energy conversion
  • Peptides
  • Piezoelectricity
  • Self-assembly


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