Continuous Infusion of Coagulation Products in Hemophilia

Angelika Batorova*, Uri Martinowitz

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Original languageEnglish
Title of host publicationTextbook of Hemophilia
Subtitle of host publicationSecond Edition
PublisherWiley-Blackwell
Pages44-51
Number of pages8
ISBN (Print)9781405169141
DOIs
StatePublished - 13 Aug 2010
Externally publishedYes

Keywords

  • Area under the curve (AUC), total amount of FVIII required
  • Bacteriologic safety of continuous infusion
  • Coagulation product continuous infusion in hemophilia
  • Continuous administration of coagulation factors - and pharmacokinetic elimination
  • Continuous infusion (CI) of recombinant FVIII in hemophilia A
  • Continuous infusion technique and concentrate stability
  • Modern methods of hemophilia treatment - requirements for quality of products
  • Modes of continuous infusion and treatment protocols
  • Pharmacokinetic evaluation, prior to planned CI - not mandatory
  • Thrombophlebitis, site of venous access - adverse event of CI of undiluted FVIII concentrates

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