Continuous high-dose intravenous desferrioxamine treatment for iron overload

Y. Sidi, M. Shaklai, E. Liban, J. Pinkhas

Research output: Contribution to journalArticlepeer-review


We describe a patient with heavy posttransfusion iron overload, to whom continuous high-dose i.v. desferrioxamine was administered shortly before his death. The administration of nearly 500 g of this agent was followed by urinary excretion of 5.4 g of iron. The chelator therapy lost its efficiency in the last of five courses and the patient eventually died as a result of cardiac and hepatic damage related to iron overload. The theoretical and practical implications of these observations are discussed.

Original languageEnglish
Pages (from-to)348-351
Number of pages4
JournalIsrael Journal of Medical Sciences
Issue number5
StatePublished - 1981


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