Conservation of brain connectivity and wiring across the mammalian class

Yaniv Assaf; Arieli Bouznach; Omri Zomet; Assaf Marom; Yossi Yovel

doi:10.1038/s41593-020-0641-7

Conservation of brain connectivity and wiring across the mammalian class

Yaniv Assaf^*, Arieli Bouznach, Omri Zomet, Assaf Marom, Yossi Yovel

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Abstract

Over 100 years ago, Ramon y Cajal hypothesized that two forces played a role in the evolution of mammalian brain connectivity: minimizing wiring costs and maximizing conductivity speed. Using diffusion MRI, we reconstructed the brain connectomes of 123 mammalian species. Network analysis revealed that both connectivity and the wiring cost are conserved across mammals. We describe a conservation principle that maintains the overall connectivity: species with fewer interhemispheric connections exhibit better intrahemispheric connectivity.

Original language	English
Pages (from-to)	805-808
Number of pages	4
Journal	Nature Neuroscience
Volume	23
Issue number	7
DOIs	https://doi.org/10.1038/s41593-020-0641-7
State	Published - 1 Jul 2020

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Conservation of brain connectivity and wiring across the mammalian class

Abstract

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