Consecutive appearance of corneal subepithelial infiltrates after intravitreous bevacizumab injections

Dan H. Bourla; Assaf Dotan; Dov Weinberger; Nirit Bourla; Israel Kremer

doi:10.1097/ICO.0b013e3181ba0cc7

Consecutive appearance of corneal subepithelial infiltrates after intravitreous bevacizumab injections

Dan H. Bourla, Assaf Dotan, Dov Weinberger, Nirit Bourla, Israel Kremer

Clinical Departments

Research output: Contribution to journal › Review article › peer-review

Abstract

PURPOSE:: To report a case of corneal subepithelial infiltrates appearing after intravitreous bevacizumab injections. METHODS:: A review of the patient's history and clinical examination findings in a patient who had epidemic keratoconjunctivitis more then 20 years before treatment with bevacizumab for age-related macular degeneration. RESULTS:: After the third and fourth bevacizumab injections, the patient presented with unilateral corneal subepithelial infiltrates. The infiltrates were accompanied by mild anterior chamber reaction and resolved with topical steroid treatment. CONCLUSIONS:: Treatment with intravitreous bevacizumab may precipitate an immune response leading to the appearance of corneal subepithelial infiltrates.

Original language	English
Pages (from-to)	686-687
Number of pages	2
Journal	Cornea
Volume	29
Issue number	6
DOIs	https://doi.org/10.1097/ICO.0b013e3181ba0cc7
State	Published - Jun 2010

Keywords

Bevacizumab
Infiltrates
Subepithelial

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10.1097/ICO.0b013e3181ba0cc7

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title = "Consecutive appearance of corneal subepithelial infiltrates after intravitreous bevacizumab injections",

abstract = "PURPOSE:: To report a case of corneal subepithelial infiltrates appearing after intravitreous bevacizumab injections. METHODS:: A review of the patient's history and clinical examination findings in a patient who had epidemic keratoconjunctivitis more then 20 years before treatment with bevacizumab for age-related macular degeneration. RESULTS:: After the third and fourth bevacizumab injections, the patient presented with unilateral corneal subepithelial infiltrates. The infiltrates were accompanied by mild anterior chamber reaction and resolved with topical steroid treatment. CONCLUSIONS:: Treatment with intravitreous bevacizumab may precipitate an immune response leading to the appearance of corneal subepithelial infiltrates.",

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author = "Bourla, {Dan H.} and Assaf Dotan and Dov Weinberger and Nirit Bourla and Israel Kremer",

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T1 - Consecutive appearance of corneal subepithelial infiltrates after intravitreous bevacizumab injections

AU - Bourla, Dan H.

AU - Dotan, Assaf

AU - Weinberger, Dov

AU - Bourla, Nirit

AU - Kremer, Israel

PY - 2010/6

Y1 - 2010/6

N2 - PURPOSE:: To report a case of corneal subepithelial infiltrates appearing after intravitreous bevacizumab injections. METHODS:: A review of the patient's history and clinical examination findings in a patient who had epidemic keratoconjunctivitis more then 20 years before treatment with bevacizumab for age-related macular degeneration. RESULTS:: After the third and fourth bevacizumab injections, the patient presented with unilateral corneal subepithelial infiltrates. The infiltrates were accompanied by mild anterior chamber reaction and resolved with topical steroid treatment. CONCLUSIONS:: Treatment with intravitreous bevacizumab may precipitate an immune response leading to the appearance of corneal subepithelial infiltrates.

AB - PURPOSE:: To report a case of corneal subepithelial infiltrates appearing after intravitreous bevacizumab injections. METHODS:: A review of the patient's history and clinical examination findings in a patient who had epidemic keratoconjunctivitis more then 20 years before treatment with bevacizumab for age-related macular degeneration. RESULTS:: After the third and fourth bevacizumab injections, the patient presented with unilateral corneal subepithelial infiltrates. The infiltrates were accompanied by mild anterior chamber reaction and resolved with topical steroid treatment. CONCLUSIONS:: Treatment with intravitreous bevacizumab may precipitate an immune response leading to the appearance of corneal subepithelial infiltrates.

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Consecutive appearance of corneal subepithelial infiltrates after intravitreous bevacizumab injections

Abstract

Keywords

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