Abstract
This is the protocol for a review and there is no abstract. The objectives are as follows: The primary objective is to compare the effects of pneumococcal conjugated vaccines (PCV) alone or added to a pneumococcal polysaccharide vaccine (PPSV) versus PPSV alone for the prevention of any pneumonia. Secondary objectives are: to compare the effect of PCV versus PPSV vaccine on any IPD and IPD caused by VT serotypes; to compare the effect of PCV versus PPSV vaccine on VT pneumonia and any pneumonia requiring hospitalisation; to examine the effects of PCV versus PPSV on immunological outcomes (antibodies level; opsonophagocytic activity); to compare the effect of PCV versus PPSV on serotype replacement; and to compare the adverse events caused by PCV to the adverse events caused by PPSV.
Original language | English |
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Article number | CD012306 |
Journal | Cochrane Database of Systematic Reviews |
Volume | 2016 |
Issue number | 8 |
DOIs | |
State | Published - 4 Aug 2016 |
Externally published | Yes |