TY - JOUR
T1 - Congenital hypofibrinogenemia in pregnancy
T2 - Report of two cases and review of the literature
AU - Frenkel, Evgenia
AU - Duksin, Chen
AU - Herman, Arie
AU - Sherman, Dan J.
PY - 2004/11
Y1 - 2004/11
N2 - Fibrinogen abnormalities have been implicated in many adverse pregnancy outcomes, mainly spontaneous abortion, placental abruption, and postpartum hemorrhage. Two new cases of congenital hypofibrinogenemia in pregnancy are reported detailing their obstetric course and management. The relevant obstetric and hematologic literature is reviewed, including previous case reports and studies concerning the mechanisms of pregnancy complications. Suggestions for treatment guidelines and management strategies are detailed.
AB - Fibrinogen abnormalities have been implicated in many adverse pregnancy outcomes, mainly spontaneous abortion, placental abruption, and postpartum hemorrhage. Two new cases of congenital hypofibrinogenemia in pregnancy are reported detailing their obstetric course and management. The relevant obstetric and hematologic literature is reviewed, including previous case reports and studies concerning the mechanisms of pregnancy complications. Suggestions for treatment guidelines and management strategies are detailed.
UR - http://www.scopus.com/inward/record.url?scp=7044227596&partnerID=8YFLogxK
U2 - 10.1097/01.ogx.0000143774.04144.b9
DO - 10.1097/01.ogx.0000143774.04144.b9
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.systematicreview???
C2 - 15502629
AN - SCOPUS:7044227596
SN - 0029-7828
VL - 59
SP - 775
EP - 779
JO - Obstetrical and Gynecological Survey
JF - Obstetrical and Gynecological Survey
IS - 11
ER -