Concentration of ciprofloxacin in human prostatic tissue after oral administration

M. Dan; J. Golomb; A. Gorea; Z. Braf; S. A. Berger

doi:10.1128/AAC.30.1.88

Concentration of ciprofloxacin in human prostatic tissue after oral administration

M. Dan, J. Golomb, A. Gorea, Z. Braf, S. A. Berger

Tel Aviv Sourasky Medical Center

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Concomitant concentrations of ciprofloxacin in serum, urine, and prostatic tissue were determined in 15 patients after single oral doses of 750 mg. Levels in tissue ranged from 0.6 to 4.18 μg/g, and therapeutic concentrations were demonstrable for up to 9 h after administration. The mean ratio of tissue to serum concentration was 0.93 ± 0.08 (standard error).

Original language	English
Pages (from-to)	88-89
Number of pages	2
Journal	Antimicrobial Agents and Chemotherapy
Volume	30
Issue number	1
DOIs	https://doi.org/10.1128/AAC.30.1.88
State	Published - 1986
Externally published	Yes

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title = "Concentration of ciprofloxacin in human prostatic tissue after oral administration",

abstract = "Concomitant concentrations of ciprofloxacin in serum, urine, and prostatic tissue were determined in 15 patients after single oral doses of 750 mg. Levels in tissue ranged from 0.6 to 4.18 μg/g, and therapeutic concentrations were demonstrable for up to 9 h after administration. The mean ratio of tissue to serum concentration was 0.93 ± 0.08 (standard error).",

author = "M. Dan and J. Golomb and A. Gorea and Z. Braf and Berger, {S. A.}",

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AU - Braf, Z.

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AB - Concomitant concentrations of ciprofloxacin in serum, urine, and prostatic tissue were determined in 15 patients after single oral doses of 750 mg. Levels in tissue ranged from 0.6 to 4.18 μg/g, and therapeutic concentrations were demonstrable for up to 9 h after administration. The mean ratio of tissue to serum concentration was 0.93 ± 0.08 (standard error).

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Concentration of ciprofloxacin in human prostatic tissue after oral administration

Abstract

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