Concentrated Aqueous Sodium Tosylate as Green Medium for Alkene Oxidation and Nucleophilic Substitution Reactions

Tal Sela, Xiaoxi Lin, Arkadi Vigalok*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

A hydrotropic solution of highly concentrated sodium tosylate (NaOTs) can be used as a recyclable medium for the environmentally benign oxidation of conjugated alkenes with H2O2. Both uncatalyzed and metal-catalyzed reactions provided the corresponding oxidation products in higher yields than in pure water or many common organic solvents.

Original languageEnglish
Pages (from-to)11609-11612
Number of pages4
JournalJournal of Organic Chemistry
Volume82
Issue number21
DOIs
StatePublished - 3 Nov 2017

Funding

FundersFunder number
BIKURA
Foundation for Ichthyosis and Related Skin Types
Israel Science Foundation

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