Computer-assisted image analysis of small cell lymphoma of the thyroid gland. Comparison of nuclear parameters of small lymphocytes in lymphomas and Hashimoto's thyroiditis

S. Eldar; E. Sabo; A. Cohen; I. Misselevich; O. Cohen; J. Kelner; C. Mor; J. Shvero; R. Feinmesser; J. Shibi; M. Shabtai; J. Bejar; J. H. Boss

doi:10.1016/S0895-6111(98)00056-1

Computer-assisted image analysis of small cell lymphoma of the thyroid gland. Comparison of nuclear parameters of small lymphocytes in lymphomas and Hashimoto's thyroiditis

S. Eldar^*, E. Sabo, A. Cohen, I. Misselevich, O. Cohen, J. Kelner, C. Mor, J. Shvero, R. Feinmesser, J. Shibi, M. Shabtai, J. Bejar, J. H. Boss

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The nuclear parameters of the small lymphocytes in nine cases of small cell lymphomas of the thyroid gland and 17 cases of Hashimoto's thyroidiris were assessed by computer-assisted image analysis. The nuclear area, maximal, minimal and averaged Ferret diameters, perimeter, regularity factor and elongation factor were gauged. Statistically, the nuclear area was ascertained to be the optimum descriptor discriminating between small neoplastic and reactive lymphocytes. Application of a novel variable, combining a nuclear area cut-off value of 14 μm² with a nuclear averaged Ferret diameter cut-off value of 4.5 μ, allows for the distinction - with a high degree of sensitivity and specificity - between small neoplastic lymphocytes in thyroidal lymphomas and the reactive lymphocytes in Hashimoto's thyroiditis.

Original language	English
Pages (from-to)	479-488
Number of pages	10
Journal	Computerized Medical Imaging and Graphics
Volume	22
Issue number	6
DOIs	https://doi.org/10.1016/S0895-6111(98)00056-1
State	Published - Nov 1998
Externally published	Yes

Keywords

Hashimoto's thyroidiris
Histomorphometry
Malignant lymphoma
Nuclear parameters of small neoplastic and reactive lymphocytes
Small cell lymphoma of the thyroid gland

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S0895-6111(98)00056-1

Cite this

Eldar, S., Sabo, E., Cohen, A., Misselevich, I., Cohen, O., Kelner, J., Mor, C., Shvero, J., Feinmesser, R., Shibi, J., Shabtai, M., Bejar, J., & Boss, J. H. (1998). Computer-assisted image analysis of small cell lymphoma of the thyroid gland. Comparison of nuclear parameters of small lymphocytes in lymphomas and Hashimoto's thyroiditis. Computerized Medical Imaging and Graphics, 22(6), 479-488. https://doi.org/10.1016/S0895-6111(98)00056-1

@article{3269de11f3224026bf5a7d780a6775cc,

title = "Computer-assisted image analysis of small cell lymphoma of the thyroid gland. Comparison of nuclear parameters of small lymphocytes in lymphomas and Hashimoto's thyroiditis",

abstract = "The nuclear parameters of the small lymphocytes in nine cases of small cell lymphomas of the thyroid gland and 17 cases of Hashimoto's thyroidiris were assessed by computer-assisted image analysis. The nuclear area, maximal, minimal and averaged Ferret diameters, perimeter, regularity factor and elongation factor were gauged. Statistically, the nuclear area was ascertained to be the optimum descriptor discriminating between small neoplastic and reactive lymphocytes. Application of a novel variable, combining a nuclear area cut-off value of 14 μm2 with a nuclear averaged Ferret diameter cut-off value of 4.5 μ, allows for the distinction - with a high degree of sensitivity and specificity - between small neoplastic lymphocytes in thyroidal lymphomas and the reactive lymphocytes in Hashimoto's thyroiditis.",

keywords = "Hashimoto's thyroidiris, Histomorphometry, Malignant lymphoma, Nuclear parameters of small neoplastic and reactive lymphocytes, Small cell lymphoma of the thyroid gland",

author = "S. Eldar and E. Sabo and A. Cohen and I. Misselevich and O. Cohen and J. Kelner and C. Mor and J. Shvero and R. Feinmesser and J. Shibi and M. Shabtai and J. Bejar and Boss, {J. H.}",

year = "1998",

month = nov,

doi = "10.1016/S0895-6111(98)00056-1",

language = "אנגלית",

volume = "22",

pages = "479--488",

journal = "Computerized Medical Imaging and Graphics",

issn = "0895-6111",

publisher = "Elsevier Ltd.",

number = "6",

}

Eldar, S, Sabo, E, Cohen, A, Misselevich, I, Cohen, O, Kelner, J, Mor, C, Shvero, J , Feinmesser, R, Shibi, J, Shabtai, M, Bejar, J & Boss, JH 1998, 'Computer-assisted image analysis of small cell lymphoma of the thyroid gland. Comparison of nuclear parameters of small lymphocytes in lymphomas and Hashimoto's thyroiditis', Computerized Medical Imaging and Graphics, vol. 22, no. 6, pp. 479-488. https://doi.org/10.1016/S0895-6111(98)00056-1

TY - JOUR

T1 - Computer-assisted image analysis of small cell lymphoma of the thyroid gland. Comparison of nuclear parameters of small lymphocytes in lymphomas and Hashimoto's thyroiditis

AU - Eldar, S.

AU - Sabo, E.

AU - Cohen, A.

AU - Misselevich, I.

AU - Cohen, O.

AU - Kelner, J.

AU - Mor, C.

AU - Shvero, J.

AU - Feinmesser, R.

AU - Shibi, J.

AU - Shabtai, M.

AU - Bejar, J.

AU - Boss, J. H.

PY - 1998/11

Y1 - 1998/11

N2 - The nuclear parameters of the small lymphocytes in nine cases of small cell lymphomas of the thyroid gland and 17 cases of Hashimoto's thyroidiris were assessed by computer-assisted image analysis. The nuclear area, maximal, minimal and averaged Ferret diameters, perimeter, regularity factor and elongation factor were gauged. Statistically, the nuclear area was ascertained to be the optimum descriptor discriminating between small neoplastic and reactive lymphocytes. Application of a novel variable, combining a nuclear area cut-off value of 14 μm2 with a nuclear averaged Ferret diameter cut-off value of 4.5 μ, allows for the distinction - with a high degree of sensitivity and specificity - between small neoplastic lymphocytes in thyroidal lymphomas and the reactive lymphocytes in Hashimoto's thyroiditis.

AB - The nuclear parameters of the small lymphocytes in nine cases of small cell lymphomas of the thyroid gland and 17 cases of Hashimoto's thyroidiris were assessed by computer-assisted image analysis. The nuclear area, maximal, minimal and averaged Ferret diameters, perimeter, regularity factor and elongation factor were gauged. Statistically, the nuclear area was ascertained to be the optimum descriptor discriminating between small neoplastic and reactive lymphocytes. Application of a novel variable, combining a nuclear area cut-off value of 14 μm2 with a nuclear averaged Ferret diameter cut-off value of 4.5 μ, allows for the distinction - with a high degree of sensitivity and specificity - between small neoplastic lymphocytes in thyroidal lymphomas and the reactive lymphocytes in Hashimoto's thyroiditis.

KW - Hashimoto's thyroidiris

KW - Histomorphometry

KW - Malignant lymphoma

KW - Nuclear parameters of small neoplastic and reactive lymphocytes

KW - Small cell lymphoma of the thyroid gland

UR - http://www.scopus.com/inward/record.url?scp=0032216061&partnerID=8YFLogxK

U2 - 10.1016/S0895-6111(98)00056-1

DO - 10.1016/S0895-6111(98)00056-1

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0032216061

SN - 0895-6111

VL - 22

SP - 479

EP - 488

JO - Computerized Medical Imaging and Graphics

JF - Computerized Medical Imaging and Graphics

IS - 6

ER -

Computer-assisted image analysis of small cell lymphoma of the thyroid gland. Comparison of nuclear parameters of small lymphocytes in lymphomas and Hashimoto's thyroiditis

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this