Computed tomography brain changes in Parkinsonian dementia

R. Inzelberg*, T. Treves, I. Reider, I. Gerlenter, A. D. Korczyn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In order to evaluate the relationship between brain atrophy and the motor and cognitive function in Parkinson's disease, we have evaluated CT changes in 132 consecutive patients and compared them to measures of physical and mental decline, using intercorrelations and variance analysis. The result demonstrated age as a most important factor relating to brain atrophy. After correction for this determinant, it became clear that the motor and cognitive parameters were interdependent but they affected similar CT parameters. The effect of motor decline was the stronger of the two and it was the only one which correlated with cortical atrophy. The results support the notion of subcortical changes underlying the dementia of Parkinson's disease.

Original languageEnglish
Pages (from-to)535-539
Number of pages5
JournalNeuroradiology
Volume29
Issue number6
DOIs
StatePublished - Nov 1987

Keywords

  • Brain atrophy
  • Computed tomography
  • Dementia
  • Parkinson's disease
  • Tropical atrophy

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