Computational Modeling of Gene Translation and its Potential Applications in Individualized Medicine

Tamir Tuller, Hadas Zur

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Gene translation is a central cellular process in all living organisms including humans. Thus, predictive modeling of this process, based on various patient specific genomic and cellular features, should have important applications in the diagnosis and understanding of various diseases. In this chapter we survey the recent advances in modeling gene translation and its potential clinical applications.

Original languageEnglish
Title of host publicationStudies in Mechanobiology, Tissue Engineering and Biomaterials
PublisherSpringer
Pages487-503
Number of pages17
DOIs
StatePublished - 2012
Externally publishedYes

Publication series

NameStudies in Mechanobiology, Tissue Engineering and Biomaterials
Volume9
ISSN (Print)1868-2006
ISSN (Electronic)1868-2014

Keywords

  • Gene Translation
  • Individualize Medicine
  • Protein Abundance
  • Translation Efficiency
  • Translation Rate

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