@article{c16c22d80adf4f8a9bf2fa383f925994,
title = "Complications of acromegaly: thyroid and colon",
abstract = "Introduction: In acromegaly the long-term exposure to high growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels may result in specific complications in different human organs, including the thyroid gland and the colon. Materials and Methods: We will review here the evidence available regarding the characteristic thyroid and colon complications in acromegaly. Results: This review summarizes the published data observing noncancerous structural abnormalities (thyroid nodules, colonic polyps) and thyroid and colon cancer in patients diagnosed with acromegaly. Conclusion: Thyroid micro-carcinomas are probably over-diagnosed among acromegalic patients. In regard to colon cancer, there is no sufficient data to suggest that colon cancer risk is higher in acromegaly compared to the general population.",
keywords = "Acromegaly, Colon, Thyroid",
author = "Amit Tirosh and Ilan Shimon",
note = "Publisher Copyright: {\textcopyright} 2016, Springer Science+Business Media New York.",
year = "2017",
month = feb,
day = "1",
doi = "10.1007/s11102-016-0744-z",
language = "אנגלית",
volume = "20",
pages = "70--75",
journal = "Pituitary",
issn = "1386-341X",
publisher = "Springer",
number = "1",
}