Complete elimination of the extracellular 23Na NMR signal in triple quantum filtered spectra of rat hearts in the presence of shift reagents

Research output: Contribution to journalComment/debate

Abstract

A method is suggested whereby the shifted extracellular triple quantum filtered 23Na signal of an isolated organ is completely eliminated. The method is based on the long relaxation time of the triple quantum coherence and on its fast evolution rate. When the carrier frequency is set on top of the intracellular sodium signal and the time interval between the last two pullses to (12 Δv)‐l (Δv is the frequency difference between the intiracellular and the extracellular signals), a complete elimination of the extracellular 23Na signal is achieved. The method is demonstrated for isolated rat hearts and the quantification of intracellular sodium using triple quantum filtered spectroscopy is discussed.

Original languageEnglish
Pages (from-to)503-506
Number of pages4
JournalMagnetic Resonance in Medicine
Volume30
Issue number4
DOIs
StatePublished - Oct 1993

Keywords

  • Na NMR
  • heart
  • multiple quantum NMR

Fingerprint

Dive into the research topics of 'Complete elimination of the extracellular 23Na NMR signal in triple quantum filtered spectra of rat hearts in the presence of shift reagents'. Together they form a unique fingerprint.

Cite this