Comparison of two techniques for target motion evaluation based on 4DCT images

Yulia Lyatskaya*, Kira Rehfeld, Dnyanesh V. Kadam, Hale Caglar, Aaron Allen, Lee M. Chin, Joseph H. Killoran

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Two techniques for target motion characterisation based on 4DCT images were evaluated: calculation of the conformality index and a technique based on image subtraction. The outputs for both techniques were shown to correlate with target displacement, indicating the applicability of these techniques for motion characterisation. While conformality index calculation requires target delineation (a time-consuming and subjective process), image subtraction is automatic and objective. In addition, the image subtraction method produces a visual representation of the areas where motion is present between different phases. The procedure has potential for automatic internal target volume definition for radiotherapy treatment purposes.

Original languageEnglish
Pages (from-to)117-137
Number of pages21
JournalInternational Journal of Biomedical Engineering and Technology
Issue number2-3
StatePublished - 2012
Externally publishedYes


  • 4DCT
  • Conformality index
  • Image subtraction
  • Tumour motion


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