Comparison of the Efficacy and Longevity of Nonpenetrating Glaucoma Surgery with and without a New, Nonabsorbable Hydrophilic Implant

Elie Dahan, Emilie Ravinet, Guy J. Ben-Simon, Andre Mermoud

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND AND OBJECTIVE: To compare the efficacy and longevity of nonpenetrating glaucoma surgery with and without the use of a nonabsorbable hydrophilic implant at the Oxford Eye Centre, Johannesburg, South Africa, and the Glaucoma Unit, Jules Gonin Ophthalmic Hospital, Lausanne, Switzerland. PATIENTS AND METHODS: In a nonrandomized, prospective study between March 1997 and December 2001, 48 eyes of 32 patients aged 18 to 86 years with primary open-angle glaucoma underwent nonpenetrating glaucoma surgery; 25 eyes with the implant and 23 eyes without it. Intraocular pressure (IOP) was recorded preoperatively and postoperatively at 1, 7, and 14 days, at 1, 3, and 6 months, and thereafter every 6 months. RESULTS: The mean preoperative IOP was 27.5 ± 11.8 mm Hg (range, 20 to 64 mm Hg) in the implant group and 24.8 ± 7.1 mm Hg (range, 16 to 38 mm Hg) in the control group. During the first 18 months of follow-up, both groups showed identical IOP progression and the mean IOP remained less than 14 mm Hg. After 2 years of follow-up, the IOP started to rise in the control group but remained stable in the implant group. After 30 months, the mean IOP was 12.4 ± 2 mm Hg and the IOP decrease in percentage was 62% ± 6% in the implant group (n = 13) versus 16.1 ± 3 mm Hg and 34% ± 13% in the control group (n = 15) (mean IOP, P = .0022; mean IOP decrease in percentage, P = .01). CONCLUSIONS: During the first 18 months, there was no difference in the outcomes between the two groups. After 2 years of follow-up, the mean IOP was lower and the IOP decrease in percentage was greater in the implant group compared with the control group.

Original languageEnglish
Pages (from-to)457-463
Number of pages7
JournalOphthalmic Surgery Lasers and Imaging
Volume34
Issue number6
StatePublished - Nov 2003
Externally publishedYes

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