Comparison of the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo)

Onofrio A. Catalano, Lale Umutlu, Niccolo Fuin, Matthew Louis Hibert, Michele Scipioni, Stefano Pedemonte, Mark Vangel, Andreea Maria Catana, Ken Herrmann, Felix Nensa, David Groshar, Umar Mahmood, Bruce R. Rosen, Ciprian Catana

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To compare the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo). Methods: MoCo PET/DCE-MRI of the upper abdomen was acquired in 44 consecutive oncologic patients and compared with non-MoCo PET/MRI. SUVmax and MTV of FDG-avid upper abdominal malignant lesions were assessed on MoCo and non-MoCo PET images. Image quality was compared between MoCo DCE-MRI and non-MoCo CE-MRI, and between fused MoCo PET/MRI and fused non-MoCo PET/MRI images. Results: MoCo PET resulted in higher SUVmax (10.8 ± 5.45) than non-MoCo PET (9.62 ± 5.42) and lower MTV (35.55 ± 141.95 cm 3 ) than non-MoCo PET (38.11 ± 198.14 cm 3 ; p < 0.005 for both). The quality of MoCo DCE-MRI images (4.73 ± 0.5) was higher than that of non-MoCo CE-MRI images (4.53±0.71; p = 0.037). The quality of fused MoCo-PET/MRI images (4.96 ± 0.16) was higher than that of fused non-MoCo PET/MRI images (4.39 ± 0.66; p < 0.005). Conclusion: MoCo PET/MRI provided qualitatively better images than non-MoCo PET/MRI, and upper abdominal malignant lesions demonstrated higher SUVmax and lower MTV on MoCo PET/MRI.

Original languageEnglish
Pages (from-to)2147-2154
Number of pages8
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Volume45
Issue number12
DOIs
StatePublished - 1 Nov 2018

Keywords

  • Abdomen
  • Oncology
  • PET/MRI
  • Respiratory motion correction

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