Comparison of polyclonal antiserum versus monoclonal antibodies for the rapid diagnosis of influenza A virus infections by immunofluorescence in clinical specimens

I. Shalit; P. A. McKee; H. Beauchamp; J. L. Waner

doi:10.1128/jcm.22.5.877-879.1985

Comparison of polyclonal antiserum versus monoclonal antibodies for the rapid diagnosis of influenza A virus infections by immunofluorescence in clinical specimens

I. Shalit, P. A. McKee, H. Beauchamp, J. L. Waner

University of Oklahoma

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A pool of monoclonal antibodies was compared with polyclonal antiserum for the rapid detection of influenza A virus in 28 clinical specimens by immunofluorescence. Monoclonal antibodies showed higher sensitivity (69 versus 46%) and accuracy (86 versus 75%) and easier slide interpretation than did polyclonal antiserum. The procedure proved useful for rapid detection of a community outbreak of influenza A virus infection.

Original language	English
Pages (from-to)	877-879
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	22
Issue number	5
DOIs	https://doi.org/10.1128/jcm.22.5.877-879.1985
State	Published - 1985
Externally published	Yes

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10.1128/jcm.22.5.877-879.1985

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AB - A pool of monoclonal antibodies was compared with polyclonal antiserum for the rapid detection of influenza A virus in 28 clinical specimens by immunofluorescence. Monoclonal antibodies showed higher sensitivity (69 versus 46%) and accuracy (86 versus 75%) and easier slide interpretation than did polyclonal antiserum. The procedure proved useful for rapid detection of a community outbreak of influenza A virus infection.

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Comparison of polyclonal antiserum versus monoclonal antibodies for the rapid diagnosis of influenza A virus infections by immunofluorescence in clinical specimens

Abstract

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