Comparison of placental isoferritin levels in maternal serum and coelomic and amniotic fluids during first trimester human gestation

R. Maymon, E. Jauniaux, C. Rodeck, L. Zaspin, C. Moroz*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Placental isoferritin (PLF) is present in serum at high concentrations throughout normal gestation. The current study compared PLF concentrations in first trimester maternal serum with those of amniotic and coelomic fluids in 25 healthy, pregnant women. Use of a specific enzyme-linked immunosorbent assay indicated concentrations high (22 ± 3 U/ml) in maternal serum, whereas significantly lower values were detected in both coelomic and amniotic fluids (5 ± 2 and 3 ± 2 U/ml, respectively, P < 0.005). It was further demonstrated that when pure PLF was added to amniotic and coelomic fluids, the PLF levels remained low in each compartment, suggesting that bioproducts produced inside the gestational sac may interfere with the PLF immunoassay.

Original languageEnglish
Pages (from-to)1044-1046
Number of pages3
JournalHuman Reproduction
Volume13
Issue number4
DOIs
StatePublished - 1998

Keywords

  • Amniotic fluid
  • Coelomic fluid
  • Placental isoferritin
  • Pregnancy

Fingerprint

Dive into the research topics of 'Comparison of placental isoferritin levels in maternal serum and coelomic and amniotic fluids during first trimester human gestation'. Together they form a unique fingerprint.

Cite this