TY - JOUR
T1 - Comparison between invasive cardiac output and left ventricular assist device flow parameter
AU - Segev, Amitai
AU - Copeland, Viana
AU - Sokolski, Mateusz
AU - Azaria, Sivan
AU - Morgan, Avi
AU - Maor, Elad
AU - Jura, Maksym
AU - Wilk, Mateusz
AU - Przybylski, Roman
AU - Freimark, Dov
AU - Ishay, Rotem Tal Ben
AU - Regev, Udi
AU - Fardman, Alexander
AU - Grupper, Avishay
N1 - Publisher Copyright:
© The Author(s) 2024. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery.
PY - 2024/11/1
Y1 - 2024/11/1
N2 - OBJECTIVES: To evaluate the correlation between left ventricular assist device flow parameter and invasive cardiac output measurements. METHODS: We retrospectively evaluated right heart catheterization examinations performed in left ventricular assist device patients from 2 tertiary medical centres. We evaluated the correlation between cardiac output measurement methods (indirect Fick and thermodilution) and pump flow parameter using linear regression, and the agreement was graphically displayed using Bland–Altman plot technique. Clinical, echocardiographic, pump and haemodynamic parameters were compared between patients with and without discordance, defined as at least a 20% difference between measurements. RESULTS: The study population consisted of 102 patients [median age 58 (51–64), 86% males, 17 ± 12 months post left ventricular assist device implantation] with a total of 544 measurements compared. Discordance between measurements was present in 102 of 226 (45%) comparisons between indirect Fick and pump flow and in 72 of 161 (48%) between thermodilution and pump flow. A comparison of indirect Fick and left ventricular assist device exhibited a statistical correlation of R ¼ 0.751, and that of thermodilution and left ventricular assist device of R ¼ 0.789. Parameters associated with the presence of discordance between cardiac output measurements included a higher rate of aortic valve opening, lower indirect Fick and higher thermodilution cardiac output. After excluding the lowest tertile of indirect Fick cardiac output values, the correlation between measurements improved (thermodilution: R ¼ 0.879 and indirect Fick: R ¼ 0.843, P < 0.001). CONCLUSIONS: The current left ventricular assist device flow parameter provides an estimation of cardiac output that correlates well with indirect Fick and exhibits the strongest correlation with thermodilution. This correlation was stronger after excluding lower cardiac output values.
AB - OBJECTIVES: To evaluate the correlation between left ventricular assist device flow parameter and invasive cardiac output measurements. METHODS: We retrospectively evaluated right heart catheterization examinations performed in left ventricular assist device patients from 2 tertiary medical centres. We evaluated the correlation between cardiac output measurement methods (indirect Fick and thermodilution) and pump flow parameter using linear regression, and the agreement was graphically displayed using Bland–Altman plot technique. Clinical, echocardiographic, pump and haemodynamic parameters were compared between patients with and without discordance, defined as at least a 20% difference between measurements. RESULTS: The study population consisted of 102 patients [median age 58 (51–64), 86% males, 17 ± 12 months post left ventricular assist device implantation] with a total of 544 measurements compared. Discordance between measurements was present in 102 of 226 (45%) comparisons between indirect Fick and pump flow and in 72 of 161 (48%) between thermodilution and pump flow. A comparison of indirect Fick and left ventricular assist device exhibited a statistical correlation of R ¼ 0.751, and that of thermodilution and left ventricular assist device of R ¼ 0.789. Parameters associated with the presence of discordance between cardiac output measurements included a higher rate of aortic valve opening, lower indirect Fick and higher thermodilution cardiac output. After excluding the lowest tertile of indirect Fick cardiac output values, the correlation between measurements improved (thermodilution: R ¼ 0.879 and indirect Fick: R ¼ 0.843, P < 0.001). CONCLUSIONS: The current left ventricular assist device flow parameter provides an estimation of cardiac output that correlates well with indirect Fick and exhibits the strongest correlation with thermodilution. This correlation was stronger after excluding lower cardiac output values.
KW - Cardiac output
KW - Fick
KW - Left ventricular assist device
KW - Left ventricular assist device flow
KW - Thermodilution
UR - http://www.scopus.com/inward/record.url?scp=85208713659&partnerID=8YFLogxK
U2 - 10.1093/ejcts/ezae383
DO - 10.1093/ejcts/ezae383
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C2 - 39453988
AN - SCOPUS:85208713659
SN - 1010-7940
VL - 66
JO - European Journal of Cardio-thoracic Surgery
JF - European Journal of Cardio-thoracic Surgery
IS - 5
M1 - ezae383
ER -