Comparative Evaluation of Mitral Valve Strain by Deformation Tracking in 3D-Echocardiography

S. Ben Zekry, G. Lawrie, S. Little, W. Zoghbi, J. Freeman, A. Jajoo, S. Jain, J. He, A. Martynenko, R. Azencott*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We present new algorithms to compute patient specific strain maps for mitral valve leaflets, by tracking and modeling deformations of the mitral valve apparatus in 3D echocardiography. We can then quantify comparisons of mitral leaflets strain maps between normal patients and cases of mitral valve prolapse or regurgitation. For patients with mitral valve regurgitation, we compare mitral leaflets strain maps between pre-surgery and post-surgery, to quantify the strain reduction due to mitral valve repair surgery.

Original languageEnglish
Pages (from-to)402-412
Number of pages11
JournalCardiovascular Engineering and Technology
Issue number4
StatePublished - Dec 2012
Externally publishedYes


FundersFunder number
John and Marynane McCormack Cardiology Fund


    • 3D-echocardiography
    • Deformable shapes
    • Diffeomorphic tracking
    • Human mitral valve
    • Leaflet tissue strain


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