Combined effect of inhaled verapamil and sodium cromoglycate on the airway response to hypertonic saline

S. Kivity*, J. Yarchovsky, J. Greif, M. Topilsky

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We evaluated the airway effect of inhaled verapamil by comparing it to aerosolized sodium cromoglycate. Airway hyperreactivity was assessed using inhaled hypertonic saline. Sodium cromoglycate prevented bronchoconstriction in all the patients. Inhaled verapamil induced significant bronchial constriction in two patients. The combination of verapamil with sodium cromoglycate was as effective as sodium cromoglycate. It was concluded that inhaled verapamil is not effective in preventing bronchoconstriction induced by hypertonic saline.

Original languageEnglish
Pages (from-to)163-165
Number of pages3
JournalAnnals of Allergy
Volume64
Issue number2 I
StatePublished - 1990
Externally publishedYes

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