Combined adriamycin, vincristine, and methotrexate. In advanced, adult, soft tissue sarcoma

J. H. Kaufman, R. Catane, H. O. Douglass

Research output: Contribution to journalArticlepeer-review

Abstract

Combination chemotherapy with VAM (vincristine, adriamycin, and high dose methotrexate) in adult soft tissue sarcoma produced 3 responders of 14 patients, with a duration of 2, 6, and 24 mth. The addition of DTIC (dimethyl triazeno imidazole carboxamide), VAM DIC, gave 2 responders of 5 cases for 6 mth. While the 21% response with VAM was disappointing, the 40% response with VAM DIC seems to confirm the effectiveness of DTIC in combination with adriamycin in sarcoma.

Original languageEnglish
Pages (from-to)742-743
Number of pages2
JournalNew York State Journal of Medicine
Volume77
Issue number5
StatePublished - 1977
Externally publishedYes

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