TY - JOUR
T1 - Combined adriamycin, vincristine, and methotrexate. In advanced, adult, soft tissue sarcoma
AU - Kaufman, J. H.
AU - Catane, R.
AU - Douglass, H. O.
PY - 1977
Y1 - 1977
N2 - Combination chemotherapy with VAM (vincristine, adriamycin, and high dose methotrexate) in adult soft tissue sarcoma produced 3 responders of 14 patients, with a duration of 2, 6, and 24 mth. The addition of DTIC (dimethyl triazeno imidazole carboxamide), VAM DIC, gave 2 responders of 5 cases for 6 mth. While the 21% response with VAM was disappointing, the 40% response with VAM DIC seems to confirm the effectiveness of DTIC in combination with adriamycin in sarcoma.
AB - Combination chemotherapy with VAM (vincristine, adriamycin, and high dose methotrexate) in adult soft tissue sarcoma produced 3 responders of 14 patients, with a duration of 2, 6, and 24 mth. The addition of DTIC (dimethyl triazeno imidazole carboxamide), VAM DIC, gave 2 responders of 5 cases for 6 mth. While the 21% response with VAM was disappointing, the 40% response with VAM DIC seems to confirm the effectiveness of DTIC in combination with adriamycin in sarcoma.
UR - http://www.scopus.com/inward/record.url?scp=0017603171&partnerID=8YFLogxK
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AN - SCOPUS:0017603171
VL - 77
SP - 742
EP - 743
JO - New York State Journal of Medicine
JF - New York State Journal of Medicine
SN - 0028-7628
IS - 5
ER -