Combination chemotherapy with VAM (vincristine, adriamycin, and high dose methotrexate) in adult soft tissue sarcoma produced 3 responders of 14 patients, with a duration of 2, 6, and 24 mth. The addition of DTIC (dimethyl triazeno imidazole carboxamide), VAM DIC, gave 2 responders of 5 cases for 6 mth. While the 21% response with VAM was disappointing, the 40% response with VAM DIC seems to confirm the effectiveness of DTIC in combination with adriamycin in sarcoma.
|Number of pages||2|
|Journal||New York State Journal of Medicine|
|State||Published - 1977|