Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease

Judith Wellens; Matthew Edmans; Uri Obolski; Colleen Gc McGregor; Peter Simmonds; Marc Turner; Lisa Jarvis; Donal Skelly; Susanna Dunachie; Eleanor Barnes; David W. Eyre; Jean Frederic Colombel; Serre Yu Wong; Paul Klenerman; James O. Lindsay; Jack Satsangi; Craig P. Thompson

doi:10.1136/gutjnl-2021-326312

Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease

Judith Wellens, Matthew Edmans, Uri Obolski, Colleen Gc McGregor, Peter Simmonds, Marc Turner, Lisa Jarvis, Donal Skelly, Susanna Dunachie, Eleanor Barnes, David W. Eyre, Jean Frederic Colombel, Serre Yu Wong, Paul Klenerman, James O. Lindsay, Jack Satsangi, Craig P. Thompson

School of Public Health

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	1919-1922
Number of pages	4
Journal	Gut
Volume	71
Issue number	9
DOIs	https://doi.org/10.1136/gutjnl-2021-326312
State	Published - 1 Sep 2022

Keywords

IBD
immune response
infectious disease

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1136/gutjnl-2021-326312

Cite this

Wellens, J., Edmans, M., Obolski, U., McGregor, C. G., Simmonds, P., Turner, M., Jarvis, L., Skelly, D., Dunachie, S., Barnes, E., Eyre, D. W., Colombel, J. F., Wong, S. Y., Klenerman, P., Lindsay, J. O., Satsangi, J., & Thompson, C. P. (2022). Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease. Gut, 71(9), 1919-1922. https://doi.org/10.1136/gutjnl-2021-326312

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title = "Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease",

keywords = "IBD, immune response, infectious disease",

author = "Judith Wellens and Matthew Edmans and Uri Obolski and McGregor, {Colleen Gc} and Peter Simmonds and Marc Turner and Lisa Jarvis and Donal Skelly and Susanna Dunachie and Eleanor Barnes and Eyre, {David W.} and Colombel, {Jean Frederic} and Wong, {Serre Yu} and Paul Klenerman and Lindsay, {James O.} and Jack Satsangi and Thompson, {Craig P.}",

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doi = "10.1136/gutjnl-2021-326312",

language = "אנגלית",

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Wellens, J, Edmans, M, Obolski, U, McGregor, CG, Simmonds, P, Turner, M, Jarvis, L, Skelly, D, Dunachie, S, Barnes, E, Eyre, DW, Colombel, JF, Wong, SY, Klenerman, P, Lindsay, JO, Satsangi, J & Thompson, CP 2022, 'Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease', Gut, vol. 71, no. 9, pp. 1919-1922. https://doi.org/10.1136/gutjnl-2021-326312

Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease. / Wellens, Judith; Edmans, Matthew; Obolski, Uri et al.

In: Gut, Vol. 71, No. 9, 01.09.2022, p. 1919-1922.

Research output: Contribution to journal › Letter › peer-review

TY - JOUR

T1 - Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease

AU - Wellens, Judith

AU - Edmans, Matthew

AU - Obolski, Uri

AU - McGregor, Colleen Gc

AU - Simmonds, Peter

AU - Turner, Marc

AU - Jarvis, Lisa

AU - Skelly, Donal

AU - Dunachie, Susanna

AU - Barnes, Eleanor

AU - Eyre, David W.

AU - Colombel, Jean Frederic

AU - Wong, Serre Yu

AU - Klenerman, Paul

AU - Lindsay, James O.

AU - Satsangi, Jack

AU - Thompson, Craig P.

PY - 2022/9/1

Y1 - 2022/9/1

KW - IBD

KW - immune response

KW - infectious disease

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U2 - 10.1136/gutjnl-2021-326312

DO - 10.1136/gutjnl-2021-326312

M3 - מזכר

C2 - 34911744

AN - SCOPUS:85133845265

VL - 71

SP - 1919

EP - 1922

JO - Gut

JF - Gut

SN - 0017-5749

IS - 9

ER -

Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease

Keywords

UN SDGs

Access to Document

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Cite this