Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease

Judith Wellens; Matthew Edmans; Uri Obolski; Colleen G.C. McGregor; Peter Simmonds; Marc Turner; Lisa Jarvis; Donal Skelly; Susanna Dunachie; Eleanor Barnes; David W. Eyre; Jean Frederic Colombel; Serre Yu Wong; Paul Klenerman; James O. Lindsay; Jack Satsangi; Craig P. Thompson

doi:10.1136/gutjnl-2021-326312

Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease

Judith Wellens, Matthew Edmans, Uri Obolski, Colleen G.C. McGregor, Peter Simmonds, Marc Turner, Lisa Jarvis, Donal Skelly, Susanna Dunachie, Eleanor Barnes, David W. Eyre, Jean Frederic Colombel, Serre Yu Wong, Paul Klenerman, James O. Lindsay, Jack Satsangi, Craig P. Thompson

School of Public Health

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Original language	English
Pages (from-to)	1919-1922
Number of pages	4
Journal	Gut
Volume	71
Issue number	9
DOIs	https://doi.org/10.1136/gutjnl-2021-326312
State	Published - Sep 2022

Funding

Funders	Funder number
Leona M. and Harry B. Helmsley Charitable Trust	COV19-RECPLAS
KU Leuven

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1136/gutjnl-2021-326312

Cite this

Wellens, J., Edmans, M., Obolski, U., McGregor, C. G. C., Simmonds, P., Turner, M., Jarvis, L., Skelly, D., Dunachie, S., Barnes, E., Eyre, D. W., Colombel, J. F., Wong, S. Y., Klenerman, P., Lindsay, J. O., Satsangi, J., & Thompson, C. P. (2022). Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease. Gut, 71(9), 1919-1922. https://doi.org/10.1136/gutjnl-2021-326312

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title = "Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease",

author = "Judith Wellens and Matthew Edmans and Uri Obolski and McGregor, {Colleen G.C.} and Peter Simmonds and Marc Turner and Lisa Jarvis and Donal Skelly and Susanna Dunachie and Eleanor Barnes and Eyre, {David W.} and Colombel, {Jean Frederic} and Wong, {Serre Yu} and Paul Klenerman and Lindsay, {James O.} and Jack Satsangi and Thompson, {Craig P.}",

year = "2022",

month = sep,

doi = "10.1136/gutjnl-2021-326312",

language = "אנגלית",

volume = "71",

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journal = "Gut",

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Wellens, J, Edmans, M, Obolski, U, McGregor, CGC, Simmonds, P, Turner, M, Jarvis, L, Skelly, D, Dunachie, S, Barnes, E, Eyre, DW, Colombel, JF, Wong, SY, Klenerman, P, Lindsay, JO, Satsangi, J & Thompson, CP 2022, 'Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease', Gut, vol. 71, no. 9, pp. 1919-1922. https://doi.org/10.1136/gutjnl-2021-326312

Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease. / Wellens, Judith; Edmans, Matthew; Obolski, Uri et al.
In: Gut, Vol. 71, No. 9, 09.2022, p. 1919-1922.

Research output: Contribution to journal › Article › peer-review

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AU - Obolski, Uri

AU - McGregor, Colleen G.C.

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AU - Skelly, Donal

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AU - Eyre, David W.

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Combination therapy of infliximab and thiopurines, but not monotherapy with infliximab or vedolizumab, is associated with attenuated IgA and neutralisation responses to SARS-CoV-2 in inflammatory bowel disease

Funding

UN SDGs

Access to Document

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