Color Doppler imaging of eyes with persistent fetal vasculature

Meira Neudorfer*, Michael Waisbourd, Sharon Buzi, Tamara Wygnanski-Jaffe, Chaim Stolovitch, Adiel Barak, Dafna Goldenberg, Ada Kessler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: Eyes with persistent fetal vasculature (PFV) may be mistaken for retinoblastoma and provide a diagnostic challenge. Objective: This study aimed to evaluate the role of color Doppler imaging (CDI) in children with persistent fetal vasculature. Materials and methods: Eyes with a diagnosis of PFV were evaluated by CDI. Results: Twenty eyes of 17 children were included. All had a confirmed diagnosis of PFV based on one or more of the following: clinical findings on funduscopy, characteristic findings on imaging modalities (ophthalmic gray-scale US, CT and/or MRI), typical findings observed intraoperatively, and histopathological analysis (after enucleation in one case). Blood flow within the PFV was demonstrated in 19 eyes in this series. Conclusion: CDI is a noninvasive diagnostic tool that may add useful information on the presence of blood flow within the PFV and may substantiate the diagnosis of PFV in cases of uncertainty.

Original languageEnglish
Pages (from-to)1229-1234
Number of pages6
JournalPediatric Radiology
Issue number10
StatePublished - Oct 2012


  • Children
  • Color Doppler imaging
  • Leukocoria
  • Persistent fetal vasculature
  • US


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