Collecting duct renal cell carcinoma: Clinical study of a rare tumor

D. Chao*, A. Zisman, A. J. Pantuck, B. J. Gitlitz, S. J. Freedland, J. W. Said, R. A. Figlin, A. S. Belldegrun

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Collecting duct carcinoma is a rare type of renal cell carcinoma that affects younger patients, and is associated with aggressive regional and distant spread. The clinical and pathological features of 6 patients with collecting duct carcinoma treated at a single institution are described. Materials and Methods: There were 6 patients with collecting duct carcinoma included in the University of California School of Medicine, Los Angeles, Kidney Cancer Database. Demographic, clinical, pathological and survival data were gathered. Results: Average patient age plus or minus standard deviation was 56 ± 11 years, and 5 of 6 had TNM stage IV disease. The average survival of these patients was 11.5 months (range 7 to 17). There was 1 patient who had TNM stage I disease and survived without evidence of disease at 5 years. Transient response to chemotherapy was seen in 1 patient. Conclusions: Collecting duct carcinoma is associated with poor prognosis. For the majority of patients surgical treatment will not result in a cure. Previously recommended chemotherapy and/or immunotherapy appears to have a limited role in treatment of this disease, and early detection may be the best method for prolonging patient survival.

Original languageEnglish
Pages (from-to)71-74
Number of pages4
JournalJournal of Urology
Volume167
Issue number1
DOIs
StatePublished - 2002
Externally publishedYes

Keywords

  • Carcinoma
  • Carcinoma, renal cell
  • Kidney

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