Colitis and death following gold therapy

Y. Siegman-Igra; M. Yaron; M. Siletzki; E. Schujman; T. Gilat

doi:10.1093/rheumatology/15.4.245

Colitis and death following gold therapy

Y. Siegman-Igra^*, M. Yaron, M. Siletzki, E. Schujman, T. Gilat

^*Corresponding author for this work

Clinical Departments

Research output: Contribution to journal › Article › peer-review

Abstract

Summary: A 45-year-old female with classical rheumatoid arthritis was started on Myocrisin injections. After receiving 130 mg Myocrisin (equivalent to 65 mg gold) she developed severe diarrhoea which was unresponsive to steroids, British Anti-Lewisite (B.A.L.) and all other conservative treatments. A rectal biopsy showed severe inflammation. Malabsorption of fat and carbohydrate was demonstrated. During hospitalization diarrhoea continued, she developed hypoproteinaemia and died. Post-mortem examination revealed severe lung infection with abscess formation and severe changes in the colon. Gold concentrations in different organs are reported.

Original language	English
Pages (from-to)	245-247
Number of pages	3
Journal	Rheumatology
Volume	15
Issue number	4
DOIs	https://doi.org/10.1093/rheumatology/15.4.245
State	Published - Nov 1976

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10.1093/rheumatology/15.4.245

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title = "Colitis and death following gold therapy",

abstract = "Summary: A 45-year-old female with classical rheumatoid arthritis was started on Myocrisin injections. After receiving 130 mg Myocrisin (equivalent to 65 mg gold) she developed severe diarrhoea which was unresponsive to steroids, British Anti-Lewisite (B.A.L.) and all other conservative treatments. A rectal biopsy showed severe inflammation. Malabsorption of fat and carbohydrate was demonstrated. During hospitalization diarrhoea continued, she developed hypoproteinaemia and died. Post-mortem examination revealed severe lung infection with abscess formation and severe changes in the colon. Gold concentrations in different organs are reported.",

author = "Y. Siegman-Igra and M. Yaron and M. Siletzki and E. Schujman and T. Gilat",

year = "1976",

month = nov,

doi = "10.1093/rheumatology/15.4.245",

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T1 - Colitis and death following gold therapy

AU - Siegman-Igra, Y.

AU - Yaron, M.

AU - Siletzki, M.

AU - Schujman, E.

AU - Gilat, T.

PY - 1976/11

Y1 - 1976/11

N2 - Summary: A 45-year-old female with classical rheumatoid arthritis was started on Myocrisin injections. After receiving 130 mg Myocrisin (equivalent to 65 mg gold) she developed severe diarrhoea which was unresponsive to steroids, British Anti-Lewisite (B.A.L.) and all other conservative treatments. A rectal biopsy showed severe inflammation. Malabsorption of fat and carbohydrate was demonstrated. During hospitalization diarrhoea continued, she developed hypoproteinaemia and died. Post-mortem examination revealed severe lung infection with abscess formation and severe changes in the colon. Gold concentrations in different organs are reported.

AB - Summary: A 45-year-old female with classical rheumatoid arthritis was started on Myocrisin injections. After receiving 130 mg Myocrisin (equivalent to 65 mg gold) she developed severe diarrhoea which was unresponsive to steroids, British Anti-Lewisite (B.A.L.) and all other conservative treatments. A rectal biopsy showed severe inflammation. Malabsorption of fat and carbohydrate was demonstrated. During hospitalization diarrhoea continued, she developed hypoproteinaemia and died. Post-mortem examination revealed severe lung infection with abscess formation and severe changes in the colon. Gold concentrations in different organs are reported.

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SN - 1462-0324

VL - 15

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EP - 247

JO - Rheumatology

JF - Rheumatology

IS - 4

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Colitis and death following gold therapy

Abstract

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