Colitis and death following gold therapy

Y. Siegman-Igra*, M. Yaron, M. Siletzki, E. Schujman, T. Gilat

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Summary: A 45-year-old female with classical rheumatoid arthritis was started on Myocrisin injections. After receiving 130 mg Myocrisin (equivalent to 65 mg gold) she developed severe diarrhoea which was unresponsive to steroids, British Anti-Lewisite (B.A.L.) and all other conservative treatments. A rectal biopsy showed severe inflammation. Malabsorption of fat and carbohydrate was demonstrated. During hospitalization diarrhoea continued, she developed hypoproteinaemia and died. Post-mortem examination revealed severe lung infection with abscess formation and severe changes in the colon. Gold concentrations in different organs are reported.

Original languageEnglish
Pages (from-to)245-247
Number of pages3
Issue number4
StatePublished - Nov 1976


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