Coherent activation of DNA tweezers: A "SET-RESET" logic system

Johann Elbaz, Michal Moshe, Itamar Willner

Research output: Contribution to journalArticlepeer-review


Open sesame: Aptamer-substrate complexes activate the coherent operation of two tweezers that act as a "SET-RESET" logic system. Each tweezer cycles between a fluorescent open state and a closed quenched state (Q=quencher, F=fluorophore) when triggered by adenosine monophosphate (AMP) and adenosine deaminase (AD).

Original languageEnglish
Pages (from-to)3834-3837
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number21
StatePublished - 11 May 2009
Externally publishedYes


  • Aptamers
  • DNA machinesl logic gates
  • Molecular devices
  • Tweezers


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