TY - JOUR
T1 - Cognitive dysfunction and antiphospholipid antibodies
AU - Appenzeller, Simone
AU - Lapa, Aline Tamires
AU - De Carvalho, Jozélio Freire
AU - Peres, Fernando Augusto
AU - Shoenfeld, Yehuda
N1 - Funding Information:
Dr. de Carvalho has received grant support from the Federico Foundation.
Funding Information:
Acknowledgments Dr. Appenzeller has received grant support from Fundação Apoio À Pesquisa Estado São Paulo-Brasil (FAPESP 2008/ 02917-0 and 2009/06049-6) and Conselho Nacional Pesquisa Desenvolvimento-Brasil CNPq (300447/2009-4).
PY - 2012/2
Y1 - 2012/2
N2 - Antiphospholipid syndrome (APS) is a multisystem prothrombotic condition, however, in recent years, its inflammatory nature has been studied extensively. Cerebral involvement is commonly observed in APS and results in different clinical manifestations. However, most of the studies include secondary APS. In this article, we review the prevalence, clinical characteristics, and physiopathology of cognitive impairment in patients with primary APS.
AB - Antiphospholipid syndrome (APS) is a multisystem prothrombotic condition, however, in recent years, its inflammatory nature has been studied extensively. Cerebral involvement is commonly observed in APS and results in different clinical manifestations. However, most of the studies include secondary APS. In this article, we review the prevalence, clinical characteristics, and physiopathology of cognitive impairment in patients with primary APS.
KW - Anticardiolipin antibodies
KW - Antiphospholipid antibodies
KW - Antiphospholipid syndrome
KW - Blood-brain barrier
KW - Central nervous system
KW - Cognition
KW - Cognitive dysfunction
KW - Cognitive impairment
KW - Dementia
KW - Neuroimaging
KW - SLE
KW - Systemic lupus erythematosus
UR - https://www.scopus.com/pages/publications/84857044112
U2 - 10.1007/s11926-011-0224-4
DO - 10.1007/s11926-011-0224-4
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AN - SCOPUS:84857044112
SN - 1523-3774
VL - 14
SP - 95
EP - 98
JO - Current Rheumatology Reports
JF - Current Rheumatology Reports
IS - 1
ER -