Coexistence of the antiphospholipid syndrome and abdominal aortic aneurysm

Martine Szyper-Kravitz, Arie Altman, Jozélio Freire de Carvalho, Francesca Bellisai, Mauro Galeazzi, Yael Eshet, Yehuda Shoenfeld*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The antiphospholipid syndrome is characterized by recurrent fetal loss, venous and/or arterial thrombosis, and thrombocytopenia associated with elevated titers of lupus anticoagulant and anticardiolipin antibodies. Although thrombosis is the characteristic vascular involvement in APS, the development of vascular aneurysms in patients with APS has been reported. We describe four patients with established APS who developed abdominal aortic aneurysm, and review the literature on previous published cases of arterial aneurysms developing in patients with APS. In addition, we discuss the possible pathophysiological association between APS and the development of this vascular abnormality.

Original languageEnglish
Pages (from-to)48-51
Number of pages4
JournalIsrael Medical Association Journal
Volume10
Issue number1
StatePublished - Jan 2008

Keywords

  • Abdominal aortic aneurysm
  • Antiphospholipid syndrome
  • Arterial dissection

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