Cobalt triflate catalyzed one-pot synthesis of fluorophore 1,4-dihydropyridine derivatives via Hantzsch reaction

Prasanta Ray Bagdi, R. Sidick Basha, Mohan Lal, Rajkumar Misra, Abu T. Khan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A wide variety of 1,4-dihydropyridines have been synthesized through one-pot condensation of aromatic aldehydes, β-ketoesters, cyclic 1,3-diones and ammonium acetate using cobalt triflate as a catalyst through Hantzsch reaction. Some of the salient features of the present protocol are shorter reaction time, mild reaction conditions, good yields, non-aqueous work-up, reusability of the catalyst and non-requirement of column chromatographic separation.

Original languageEnglish
Pages (from-to)1589-1598
Number of pages10
JournalJournal of the Indian Chemical Society
Volume90
Issue number10
StatePublished - Oct 2013
Externally publishedYes

Keywords

  • 1,4-dihydropyridines
  • Ammonium acetate
  • Aromatic aldehydes
  • Cobalt triflate
  • Cyclic 1,3-diketones
  • Multicomponent reaction
  • β-ketoesters

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