Coagulation factor deficiencies and pregnancy loss

Aida Inbal; Laszlo Muszbek

doi:10.1055/s-2003-38832

Coagulation factor deficiencies and pregnancy loss

Aida Inbal^*, Laszlo Muszbek

^*Corresponding author for this work

Clinical Departments

Research output: Contribution to journal › Review article › peer-review

93 Scopus citations

Abstract

Of all the coagulation factor deficiencies, only deficiency of factor XIII (FXIII) and fibrinogen are associated with pregnancy loss. FXIII deficiency and a complete or partial deficiency of fibrinogen are associated with bleeding since childhood, impaired wound repair, and recurrent spontaneous abortions. Both FXIII and fibrinogen play an essential role in placental implantation and maintenance of pregnancy. The causes of miscarriages in FXIII or fibrinogen-deficient women is discussed and an appropriate treatment advocated.

Original language	English
Pages (from-to)	171-174
Number of pages	4
Journal	Seminars in Thrombosis and Hemostasis
Volume	29
Issue number	2
DOIs	https://doi.org/10.1055/s-2003-38832
State	Published - Apr 2003

Keywords

Afibrinogenemia
Factor XIII deficiency
Miscarriages

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1055/s-2003-38832

Cite this

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title = "Coagulation factor deficiencies and pregnancy loss",

abstract = "Of all the coagulation factor deficiencies, only deficiency of factor XIII (FXIII) and fibrinogen are associated with pregnancy loss. FXIII deficiency and a complete or partial deficiency of fibrinogen are associated with bleeding since childhood, impaired wound repair, and recurrent spontaneous abortions. Both FXIII and fibrinogen play an essential role in placental implantation and maintenance of pregnancy. The causes of miscarriages in FXIII or fibrinogen-deficient women is discussed and an appropriate treatment advocated.",

keywords = "Afibrinogenemia, Factor XIII deficiency, Miscarriages",

author = "Aida Inbal and Laszlo Muszbek",

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AU - Inbal, Aida

AU - Muszbek, Laszlo

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AB - Of all the coagulation factor deficiencies, only deficiency of factor XIII (FXIII) and fibrinogen are associated with pregnancy loss. FXIII deficiency and a complete or partial deficiency of fibrinogen are associated with bleeding since childhood, impaired wound repair, and recurrent spontaneous abortions. Both FXIII and fibrinogen play an essential role in placental implantation and maintenance of pregnancy. The causes of miscarriages in FXIII or fibrinogen-deficient women is discussed and an appropriate treatment advocated.

KW - Afibrinogenemia

KW - Factor XIII deficiency

KW - Miscarriages

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AN - SCOPUS:0037394680

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Coagulation factor deficiencies and pregnancy loss

Abstract

Keywords

UN SDGs

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