Co-inflammatory roles of TGFβ1 in the presence of TNFα drive a pro-inflammatory fate in mesenchymal stem cells

Keyphrases

• Transforming Growth Factor-β 100%
• Tumor Necrosis Factor-α 100%
• Mesenchymal Stem Cells 100%
• Microenvironment 25%
• Inflammatory Mediators 25%
• Cyclooxygenase-2 25%
• CXCL8 25%
• Chemokine Ligand 2 (CCL2) 25%
• NF-B 16%
• Smad3 16%
• Inflammation 8%
• Molecular Mechanism 8%
• Protein Level 8%
• Protein Expression 8%
• Cell Migration 8%
• Interleukin-8 8%
• Inflammatory Cytokines 8%
• Superplasticity 8%
• Cooperativity 8%
• Cell Elongation 8%
• MRNA Expression 8%
• Human Mesenchymal Stem Cells (hMSCs) 8%
• Global Gene Expression Analysis 8%
• Cardiomyopathy 8%
• Tumor Niche 8%
• Soluble Factors 8%
• Breast Tumor Cells 8%
• Tumor Mass 8%
• Upstream Regulator 8%
• Protein Expression Level 8%
• Cooperative Activity 8%
• Transcriptional Program 8%
• Inflammatory Factors 8%
• Cell Scattering 8%
• Combined Stimulation 8%
• Stem Cell Activation 8%
• Bone Tumor 8%
• Smad3 Pathway 8%
• Release Factor 8%
• Health-related Conditions 8%

Biochemistry, Genetics and Molecular Biology

• Stem Cell 100%
• Tumor Necrosis Factor 100%
• Cancer Growth Factor 100%
• Fibrinogen 100%
• Mediator 25%
• Cyclooxygenase 25%
• CCL2 25%
• Kinase 16%
• Phosphotransferase 16%
• Cytokine 16%
• Protein Expression 8%
• Cooperation 8%
• Cell Function 8%
• Gene Expression Profiling 8%
• Interleukin 8 8%
• Inflammatory Cytokine 8%
• Protein Expression Level 8%
• Bone Marrow-Derived Mesenchymal Stem Cells 8%
• Release Factor 8%
• Cell Elongation 8%
• Tumor Spheroid 8%
• Messenger RNA 8%
• Anti-Inflammatory 8%
• Molecular Mechanism 8%