Clozapine for tardive dyskinesia in adolescents

Yechiel Levkovitch, Julia Kronenberg, Nehemia Kayser, Michael Zvyagelski, Bracha Gaoni, Natan Gadoth

Research output: Contribution to journalArticlepeer-review


Thousands of adolescents use neuroleptic drugs over extended periods of time for a wide range of mental disorders. One of the most severe adverse effects of neuroleptic drugs is tardive dyskinesia (TD), for which no successful treatment is currently available. Clozapine is a known atypical neuroleptic drug with few extrapyramidal side effects. It has been suggested that clozapine may be beneficial for the treatment of tardive dyskinesia in adolescents. However, the efficacy of the drug in adolescents is unknown. This report describes the beneficial effect of clozapine on tardive dyskinesia in two adolescents with schizophrenia.

Original languageEnglish
Pages (from-to)213-215
Number of pages3
JournalBrain and Development
Issue number3
StatePublished - 1995


  • Adolescence
  • Clozapine
  • Neuroleptic
  • Tardive dyskinesia


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