Abstract
Two episodes of urinary retention occurred in a 15-year-old male following administration of clomipromine given for obsessive-compulsive disorder. Improvement of behavioral symptoms along with side effects was clearly correlated with clomiparmine dosage. Severity of side effects, and their resistance to bethanechol and to phenoxybenzamine, necessitated a complete withdrawal of clomipramine. This case demonstrates that clomipramine-induced urinary retention is not limited to older individuals. Possible involvement of noncholinergic and nonadrenergic mechanisms in this adverse drug reaction is suggested.
| Original language | English |
|---|---|
| Pages (from-to) | 877-879 |
| Number of pages | 3 |
| Journal | Drug Intelligence and Clinical Pharmacy |
| Volume | 21 |
| Issue number | 11 |
| DOIs | |
| State | Published - 1987 |
| Externally published | Yes |