Clinical utility of expanded non-invasive prenatal screening compared with chromosomal microarray analysis in over 8000 pregnancies without major structural anomaly

Keyphrases

• Structural Anomalies 100%
• Clinical Utility 100%
• Chromosomal Microarray 100%
• Noninvasive Prenatal Screening 100%
• Microdeletion 21%
• Clinically Significant 10%
• Soft Markers 10%
• Abnormal Maternal Serum Screening 10%
• Rabin 5%
• Medical Center 5%
• Retrospective Cohort Study 5%
• Ultrasound 5%
• 22q11.2 Deletion Syndrome 5%
• Aneuploidy 5%
• Chromosome 13 5%
• Screening Tool 5%
• Advanced Maternal Age 5%
• Health Practitioners 5%
• Genetic Laboratory 5%
• Chromosome 18 5%
• Amniocentesis 5%
• Informed Decision-making 5%
• Invasive Testing 5%
• Chromosome Y 5%
• Prenatal Invasive Test 5%
• Theoretical Yield 5%

Medicine and Dentistry

• Array Comparative Genomic Hybridization 100%
• Prenatal Screening 100%
• Maternal Serum 10%
• Decision Making 5%
• Retrospective Cohort Study 5%
• Y Chromosome 5%
• Maternal Age 5%
• Healthcare Practitioner 5%
• Amniocentesis 5%
• Aneuploidy 5%
• Chromosome 18 5%
• Chromosome 13 5%

Biochemistry, Genetics and Molecular Biology

• Array Comparative Genomic Hybridization 100%
• Prenatal Screening 100%
• Genetics 5%
• Y Chromosome 5%
• Decision Making 5%
• Cohort Study 5%
• Chromosome 13 5%
• Maternal Age 5%
• Chromosome 18 5%
• Aneuploidy 5%