Clinical consequences of silent gastroesophageal reflux disease

Ronnie Fass, Ram Dickman

Research output: Contribution to journalReview articlepeer-review


Silent gastroesophageal reflux disease (GERD) is a very common phenomenon that involves the incidental finding of erosive esophagitis, Barrett's esophagus, and the evolution of esophageal adenocarcinoma in asymptomatic patients. The reasons for having advanced GERD without clearly identifiable symptoms are poorly understood, primarily due to lack of recognition of this important phenomenon. The clinical implications of silent GERD are vast and should provide the impetus for further research into this group of patients. Recent studies have suggested that sleep disturbances and poor quality of sleep could be the needed clues to identify individuals with silent GERD.

Original languageEnglish
Pages (from-to)195-201
Number of pages7
JournalCurrent Gastroenterology Reports
Issue number3
StatePublished - Jun 2006


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