Clinical and laboratory impact of coagulase-negative staphylococci bacteremia in preterm infants

A. Maayan-Metzger, N. Linder, D. Marom, T. Vishne, S. Ashkenazi, L. Sirota

Research output: Contribution to journalArticlepeer-review

Abstract

A retrospective evaluation of the clinical and laboratory impact of coagulase-negative staphylococci (CONS) bacteremia in preterm infants was carried out. The study population included all preterm infants (n = 31) in whom two or more blood cultures were positive for CONS within a period of 4 d, with negative blood cultures 1 wk before and 1 wk after the CONS bacteremia. Clinical manifestations and the results of laboratory tests 7 d before and after the positive blood cultures, and on the first day of sepsis, were recorded and compared. During CONS bacteremia, the infants demonstrated apnoea and bradycardia (88%) and a need for oxygen (59%) and ventilatory support (69%). Significant laboratory findings were leukopenia below 5000 cells/mm3 (12%), leukocytosis above 30000 cells/mm3 (39%), and thrombocytopenia below 150000/mm3 (25%). These clinical and laboratory manifestations differed significantly during the bacteremia infection compared with the week before and after. Conclusion: CONS bacteremia is a clinically significant infection in preterm infants, Causing episodes of apnoea and bradycardia, and a need for ventilatory support.

Original languageEnglish
Pages (from-to)690-693
Number of pages4
JournalActa Paediatrica, International Journal of Paediatrics
Volume89
Issue number6
DOIs
StatePublished - 2000

Keywords

  • Coagulase-negative staphylococci
  • Preterm infants

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