TY - JOUR
T1 - Classification of HHV-6A and HHV-6B as distinct viruses
AU - Ablashi, Dharam
AU - Agut, Henri
AU - Alvarez-Lafuente, Roberto
AU - Clark, Duncan A.
AU - Dewhurst, Stephen
AU - DiLuca, Dario
AU - Flamand, Louis
AU - Frenkel, Niza
AU - Gallo, Robert
AU - Gompels, Ursula A.
AU - Höllsberg, Per
AU - Jacobson, Steven
AU - Luppi, Mario
AU - Lusso, Paolo
AU - Malnati, Mauro
AU - Medveczky, Peter
AU - Mori, Yasuko
AU - Pellett, Philip E.
AU - Pritchett, Joshua C.
AU - Yamanishi, Koichi
AU - Yoshikawa, Tetsushi
PY - 2014/5
Y1 - 2014/5
N2 - Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A and HHV-6B, were identified. In 2012, the International Committee on Taxonomy of Viruses (ICTV) classified HHV-6A and HHV-6B as separate viruses. This review outlines several of the documented epidemiological, biological, and immunological distinctions between HHV-6A and HHV-6B, which support the ICTV classification. The utilization of virus-specific clinical and laboratory assays for distinguishing HHV-6A and HHV-6B is now required for further classification. For clarity in biological and clinical distinctions between HHV-6A and HHV-6B, scientists and physicians are herein urged, where possible, to differentiate carefully between HHV-6A and HHV-6B in all future publications.
AB - Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A and HHV-6B, were identified. In 2012, the International Committee on Taxonomy of Viruses (ICTV) classified HHV-6A and HHV-6B as separate viruses. This review outlines several of the documented epidemiological, biological, and immunological distinctions between HHV-6A and HHV-6B, which support the ICTV classification. The utilization of virus-specific clinical and laboratory assays for distinguishing HHV-6A and HHV-6B is now required for further classification. For clarity in biological and clinical distinctions between HHV-6A and HHV-6B, scientists and physicians are herein urged, where possible, to differentiate carefully between HHV-6A and HHV-6B in all future publications.
UR - http://www.scopus.com/inward/record.url?scp=84899935021&partnerID=8YFLogxK
U2 - 10.1007/s00705-013-1902-5
DO - 10.1007/s00705-013-1902-5
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AN - SCOPUS:84899935021
SN - 0304-8608
VL - 159
SP - 863
EP - 870
JO - Archives of Virology
JF - Archives of Virology
IS - 5
ER -