Classical control theory approach to enzymatic reactions

E. Gershon, R. Hiller, U. Shaked

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


In this paper we present some models of various enzymatic reaction systems amenable to analytic techniques of classical control theory. These models extend from simple and most abundant cases to more involved cases where (negative) feedback plays a major role at the level of a single enzyme reaction (including the so called 'feed-back inhibition'). Using the above models we point at the specific feedback loop at the molecular level, if it exists, of a given reaction scheme. A simple numerical analysis of an enzyme reaction system demonstrates the applicability of our approach.

Original languageEnglish
Title of host publicationEuropean Control Conference, ECC 2003
PublisherInstitute of Electrical and Electronics Engineers Inc.
Number of pages6
ISBN (Electronic)9783952417379
StatePublished - 13 Apr 2003
Event2003 European Control Conference, ECC 2003 - Cambridge, United Kingdom
Duration: 1 Sep 20034 Sep 2003

Publication series

NameEuropean Control Conference, ECC 2003


Conference2003 European Control Conference, ECC 2003
Country/TerritoryUnited Kingdom


  • Biological control systems
  • Feedback control
  • Feedback inhibition
  • Robust control


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