Cirrhotic glomerulonephritis: An underdiagnosed condition

Y. Ori, A. Korzets, J. Sandbank, B. Lurie, A. Zeidman, U. Gafter

Research output: Contribution to journalArticlepeer-review

Abstract

Glomerular pathology in liver cirrhosis is common in autopsies but is underdiagnosed antemortem The most common pathologic findings are mesangial disease with immunoglobulin A deposits, and membranoproliferative glomerulonephritis. The latter is associated, most frequently, with hepatitis C infection and cryoglobulinemia. We describe a patient with longstanding liver cirrhosis who presented with a nephritic and nephrotic syndrome. Membranoproliferative glomerulonephritis was diagnosed on kidney biopsy. There was no clinical, laboratory or histologic evidence of hepatitis C infection or cryoglobulinemia. The different aspects of 'cirrhotic glomerulonephritis' are discussed and the need for searching for this underdiagnosed condition in patients with chronic liver disease is emphasized.

Original languageEnglish
Pages (from-to)1222-1224
Number of pages3
JournalIsrael Journal of Medical Sciences
Volume32
Issue number12
StatePublished - Dec 1996
Externally publishedYes

Keywords

  • Cirrhosis
  • Glomerulonephritis

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