Circumferential and Longitudinal Strain in 3 Myocardial Layers in Normal Subjects and in Patients with Regional Left Ventricular Dysfunction

Marina Leitman*, Michael Lysiansky, Peter Lysyansky, Zvi Friedman, Vladimir Tyomkin, Therese Fuchs, Dan Adam, Ricardo Krakover, Zvi Vered

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The left ventricle is not homogenous and is composed of 3 myocardial layers. Until recently, magnetic resonance imaging has been the only noninvasive technique for detailed evaluation of the left ventricular (LV) wall. The aim of this study was to analyze strain in 3 myocardial layers using speckle-tracking echocardiography. Methods: Twenty normal subjects and 21 patients with LV dysfunction underwent echocardiography. Short-axis (for circumferential) and apical (for longitudinal strain) views were analyzed using modified speckle-tracking software enabling the analysis of strain in 3 myocardial layers. Results: In normal subjects, longitudinal and circumferential strain was highest in the endocardium and lowest in the epicardium. Longitudinal endocardial and mid layer strain was highest in the apex and lowest in the base. Epicardial longitudinal strain was homogenous over the left ventricle. Circumferential 3-layer strain was highest in the apex and lowest in the base. In patients with LV dysfunction, strain was lower, with late diastolic or double peak. Conclusions: Three-layer analysis of circumferential and longitudinal strain using speckle-tracking imaging can be performed on a clinical basis and may become an important method for the assessment of real-time, quantitative global and regional LV function.

Original languageEnglish
Pages (from-to)64-70
Number of pages7
JournalJournal of the American Society of Echocardiography
Volume23
Issue number1
DOIs
StatePublished - Jan 2010

Keywords

  • Myocardial layers
  • Speckle tracking
  • Strain

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