Chronic idiopathic granulomatous mastitis

Uriel Katz, Yair Molad, Jacob Ablin, Debby Ben-David, Daphna Paran, Mordechai Gutman, Pnina Langevitz

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We describe four women with idiopathic granulomatous mastitis, a rare benign disease. Age range was 32-40 years. Disease duration was less than 1 year in three patients and long term in the fourth. The diagnosis was based on histological findings, after extensive work-up ruled out malignancy and known causes of granulomatous mastitis. Treatment with prednisone with gradual tapering yielded a good response. Clinicians should consider the possibility of idiopathic granulomatous mastitis in young women with inflammatory breast processes and negative findings on relevant biopsy, laboratory, and imaging studies. Glucocorticoids are the treatment of choice; surgery is not recommended. Some patients require a glucocorticoid-sparing drug.

Original languageEnglish
Title of host publicationAutoimmunity, Part D
Subtitle of host publicationAutoimmune Disease, Annus Mirabilis
PublisherBlackwell Publishing Inc.
Pages603-608
Number of pages6
ISBN (Print)157331708X, 9781573317085
DOIs
StatePublished - Jun 2007

Publication series

NameAnnals of the New York Academy of Sciences
Volume1108
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632

Keywords

  • Diagnosis
  • Glucocorticoids
  • Idiopathic granulomatous mastitis
  • Methotrexate
  • Treatment

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