Chronic Fatigue: Definition and Overlap with Fibromyalgia

Galya Tanay, Yehuda Shoenfeld*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


This chapter includes a rather simplified definition and the diagnostic criteria of fibromyalgia syndrome (FMS) and a more detailed one for myalgic encephalomyelitis/chronic fatigue syndrome (CFS). Definitions will lead to a discussion on whether CFS is the same or a different illness from FMS, since a clinical overlap indeed exists between the two syndromes, and there have been notions in the literature claiming that they are variants of the same illness—called “the unitarian hypothesis.” A review of the existing literature will be presented in an attempt to delineate similarities and differences between the two syndromes.

Original languageEnglish
Title of host publicationFibromyalgia Syndrome
PublisherSpringer International Publishing
Number of pages9
ISBN (Electronic)9783030786380
ISBN (Print)9783030786373
StatePublished - 1 Jan 2021
Externally publishedYes


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