Chronic demodicosis in patients with immune dysregulation: An unexpected infectious manifestation of Signal transducer and activator of transcription (STAT)1 gain-of-function

Keyphrases

• Gain-of-function 100%
• Signal Transducer and Activator of Transcription 1 100%
• Immune Dysregulation 100%
• Demodicosis 100%
• STAT1 Gain of Function 50%
• Chronic mucocutaneous Candidiasis 33%
• Jewish Family 16%
• Retrospective Analysis 16%
• Whole Exome Sequencing 16%
• Clinical Presentation 16%
• Sanger Sequencing 16%
• Functional Studies 16%
• Regulatory T Cells 16%
• Transcriptional Repressor 16%
• Forkhead Box P3 (FOXP3) 16%
• Signal Transducer 16%
• Immunophenotyping 16%
• Patient Management 16%
• Interferon-α (IFN-α) 16%
• Age at Presentation 16%
• Gain-of-function mutation 16%
• T Cell Proliferation 16%
• Immune Parameters 16%
• Proliferation Ability 16%
• Immunogenetics 16%
• Non-consanguineous 16%
• Primary Immune Deficiency 16%
• Low Counts 16%
• Primary Antibody Deficiency 16%
• Topical Metronidazole 16%
• Ocular Demodicosis 16%
• Topical Ivermectin 16%
• Interleukin-17-producing T Cells 16%
• STAT1 Gain-of-function mutation 16%

Immunology and Microbiology

• STAT1 100%
• Immune Dysregulation 100%
• Gain of Function Mutation 33%
• Chronic Mucocutaneous Candidiasis 33%
• Whole Exome Sequencing 16%
• T Cell 16%
• Regulatory T Cell 16%
• Forkhead Transcription Factor 16%
• interferon 16%
• T Cell Proliferation 16%
• Immunodeficiency 16%
• Immunogenetics 16%
• Humoral Immune Deficiency 16%
• Dideoxynucleotide Sequencing 16%
• Interleukin 17 16%