Chronic and Acute Effects of Cigarette Smoking on Skin Blood Flow

A laser Doppler flowmeter was used to assess blood flow changes in habitu al smokers, as compared with nonsmokers, where members of both groups were young and healthy. Acute and chronic effects of cigarette smoking were meas ured by using the cutaneous postischemic reactive hyperemia test. Basic flow was recorded in four sites: forehead, postauricular, forearm, and finger. Recovery time from reactive hyperemia was longer in habitual smokers than in nonsmokers. Peak flow during reactive hyperemia was significantly lower af ter smoking. Basic blood flow during smoking did not show significant varia tion in the sites tested. The authors conclude that skin microvasculature is influenced by acute and chronic effects of cigarette smoking in young subjects; they discuss some of the possible mechanisms and their implications.