TY - JOUR
T1 - Chromosome abnormalities in infants with prune belly anomaly
T2 - Association with trisomy 18
AU - Frydman, M.
AU - Magenis, R. E.
AU - Mohandas, T. K.
AU - Kaback, M. M.
PY - 1983
Y1 - 1983
N2 - Two infants are described with 'prune belly anomaly' (PBA) and concomitant trisomy 18. Severe abdominal distention was detected prenatally in one by ultrasonographic study, and in the second child at birth. Other chromosome abnormalities previously associated with PBA also are reviewed. The prune belly anomaly constitutes a malformation sequence that is causally nonspecific and which may occur in diverse aneuploidy syndromes. Aneuploidy is important to detect in prenatally diagnosed cases in which intrauterine fetal treatment is being considered.
AB - Two infants are described with 'prune belly anomaly' (PBA) and concomitant trisomy 18. Severe abdominal distention was detected prenatally in one by ultrasonographic study, and in the second child at birth. Other chromosome abnormalities previously associated with PBA also are reviewed. The prune belly anomaly constitutes a malformation sequence that is causally nonspecific and which may occur in diverse aneuploidy syndromes. Aneuploidy is important to detect in prenatally diagnosed cases in which intrauterine fetal treatment is being considered.
UR - http://www.scopus.com/inward/record.url?scp=0020567547&partnerID=8YFLogxK
U2 - 10.1002/ajmg.1320150120
DO - 10.1002/ajmg.1320150120
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 6859114
AN - SCOPUS:0020567547
SN - 0148-7299
VL - 15
SP - 145
EP - 148
JO - American Journal of Medical Genetics
JF - American Journal of Medical Genetics
IS - 1
ER -