Chorioamnionitis associated with Crohn's disease and azathioprine treatment: A case report

Limor Helpman, David Pauzner, Joseph B. Lessing, Michael J. Kupfermine, Guy Gutman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

This paper reports a case of S. constellatus chorioamnionitis in a pregnant Crohn's disease patient who was taking azathioprine. Chorioamnionitis is a major cause of perinatal morbidity. Azathioprine, an immunosuppressive antimetabolite, is widely used to treat inflammatory bowel disease. Streptococcus constellatus is a Gram-positive bacterium that has not previously been associated with chorioamnionitis. A high index of suspicion for chorioamnionitis and unusual pathogens should be maintained in the management of obstetric patients on immunosuppressive agents.

Original languageEnglish
Pages (from-to)803-804
Number of pages2
JournalJournal of Medical Microbiology
Volume54
Issue number8
DOIs
StatePublished - Aug 2005

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