TY - JOUR
T1 - Cholinergic excitation induces activity-dependent electrophysiological and transcriptional responses in hippocampal slices
AU - Friedman, Alon
AU - Kaufer, Daniela
AU - Pavlovsky, Lev
AU - Soreq, Hermona
N1 - Funding Information:
This study has been supported by the Teva Research prize for young investigators, the Smith Psychobiology Fund and the Goldman Fund (to A.E) as well as the by the Basic Research Fund (to H.S.). All experiments were performed in accordance with institutional guidelines for animal experimentation.
PY - 1998
Y1 - 1998
N2 - To explore the correlations between short-term neurophysiological events initiated by over-activation of acetylcholine receptors, and long-lasting changes in brain function, we combined electrophysiology and PCR-based measurements in hippocampal slices or live mice subjected to stress or drug- induced cholinergic activation. Our findings reveal a common cascade of neuronal events resulting in delayed suppression of cholinergic transmission.
AB - To explore the correlations between short-term neurophysiological events initiated by over-activation of acetylcholine receptors, and long-lasting changes in brain function, we combined electrophysiology and PCR-based measurements in hippocampal slices or live mice subjected to stress or drug- induced cholinergic activation. Our findings reveal a common cascade of neuronal events resulting in delayed suppression of cholinergic transmission.
UR - http://www.scopus.com/inward/record.url?scp=0032105445&partnerID=8YFLogxK
U2 - 10.1016/S0928-4257(98)80042-9
DO - 10.1016/S0928-4257(98)80042-9
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C2 - 9789832
AN - SCOPUS:0032105445
SN - 0928-4257
VL - 92
SP - 329
EP - 335
JO - Journal of Physiology Paris
JF - Journal of Physiology Paris
IS - 3-4
ER -